Marsh Mark, Helenius Ari
Cell Biology Unit, MRC Laboratory for Molecular Cell Biology, and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.
Cell. 2006 Feb 24;124(4):729-40. doi: 10.1016/j.cell.2006.02.007.
Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells. These insights are revolutionizing our understanding of endocytosis and the movement of vesicles within cells. In addition, such insights reveal new targets for attacking viruses before they can usurp the host-cell machinery for replication.
要制定阻止病毒的策略，需要有关病毒复制周期及其与宿主生物体相互作用的详细信息。细胞生物学研究、活细胞成像和系统生物学已开始揭示动物病毒进入宿主细胞所采用的多种且略有不同的途径。这些见解正在彻底改变我们对细胞内吞作用和囊泡运动的理解。此外，这些见解还揭示了在病毒篡夺宿主细胞机制进行复制之前攻击病毒的新靶点。
Zotero 插件
