Qiao D, Hou L, Liu X
Beijing Normal University, Beijing, China.
Br J Sports Med. 2006 Mar;40(3):214-8. doi: 10.1136/bjsm.2005.020099.
To determine the effect of intermittent anaerobic exercise on physical endurance, antioxidant capacity, and lipid peroxidation of brain, heart, and skeletal muscles in mice.
Mice were made to perform intermittent (with short or long rest intervals) anaerobic swimming on six consecutive days. Body weight was monitored. Tissue total antioxidant capacity (T-AOC), superoxide dismutase (SOD), and thiobarbituric acid reaction substance (TBARS) were determined on the 2nd, 4th, and 6th day. Physical endurance was determined on day 7 by using an exhaustive swimming test and a static grasping test.
The intermittent anaerobic exercise resulted in decreased growth rate and physical endurance capacity, as indicated by less weight gain and shorter time to exhaustion during the exhaustive swimming and static grasping test (p<0.05). It also led to a higher T-AOC in muscle, heart, and brain, higher SOD activity in muscle and heart, and higher TBARS content in muscle (p<0.05). This type of exercise had no effect on brain SOD and TBARS. The changes in T-AOC in brain, muscle, and heart were all more pronounced the longer the experiment continued (p<0.05).
Intermittent anaerobic exercise reduced growth and physical endurance and increased tissue antioxidant capacity and lipid peroxidation.
确定间歇性无氧运动对小鼠身体耐力、抗氧化能力以及脑、心脏和骨骼肌脂质过氧化的影响。
使小鼠连续六天进行间歇性（短休息间隔或长休息间隔）无氧游泳。监测体重。在第2天、第4天和第6天测定组织总抗氧化能力（T-AOC）、超氧化物歧化酶（SOD）和硫代巴比妥酸反应物质（TBARS）。在第7天通过力竭游泳试验和静态抓握试验测定身体耐力。
间歇性无氧运动导致生长速率和身体耐力能力下降，表现为体重增加较少以及在力竭游泳和静态抓握试验中力竭时间较短（p<0.05）。它还导致肌肉、心脏和脑中的T-AOC升高，肌肉和心脏中的SOD活性升高，以及肌肉中的TBARS含量升高（p<0.05）。这种运动对脑SOD和TBARS没有影响。实验持续时间越长，脑、肌肉和心脏中T-AOC的变化越明显（p<0.05）。
间歇性无氧运动降低了生长和身体耐力，并增加了组织抗氧化能力和脂质过氧化。
