Shao Hong-Jun, Qing Chen, Wang Fei, Zhang Yan-Li, Luo Du-Qiang, Liu Ji-Kai
Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
J Antibiot (Tokyo). 2005 Dec;58(12):828-31. doi: 10.1038/ja.2005.111.
A new cytotoxic lanostane triterpenoid, 24(E)-3beta-hydroxylanosta-8,24-dien-26-al-21-oic acid (1), was isolated from the fruiting bodies of the mushroom Hebeloma versipelle. The structure was elucidated on the basis of spectroscopic studies including 2D NMR experiments. Compound 1 moderately inhibited the growth of several tumor cell lines (IC50 10-25.0 microg/ml).
