多器官淋巴细胞浆细胞浸润且对IgG4呈免疫反应性：IgG4相关性系统性疾病。
Lymphoplasmacytic infiltration of multiple organs with immunoreactivity for IgG4: IgG4-related systemic disease.
作者信息
Saeki Takako, Saito Akihiko, Hiura Tohru, Yamazaki Hajime, Emura Iwao, Ueno Mitsuhiro, Miyamura Syoji, Gejyo Fumitake
机构信息
Department of Internal Medicine, Nagaoka Red Cross Hospital, Nagaoka.
出版信息
Intern Med. 2006;45(3):163-7. doi: 10.2169/internalmedicine.45.1431. Epub 2006 Mar 1.
We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium. The infiltrating plasma cells had strong immunoreactivity for IgG4, even in patients without pancreatic lesions. These cases show that IgG4 is associated not only with autoimmune pancreatitis, but also with other systemic lymphoplasmacytic disease.
我们报告了三名老年男性，他们血清IgG4浓度升高，唾液腺、淋巴结、胰腺和肾间质存在多处淋巴浆细胞炎症。即使在没有胰腺病变的患者中，浸润的浆细胞对IgG4也有强烈的免疫反应性。这些病例表明，IgG4不仅与自身免疫性胰腺炎有关，还与其他系统性淋巴浆细胞疾病有关。
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