加那利群岛橄榄油摄入量与乳腺癌风险：一项基于人群的病例对照研究。

Olive oil consumption and risk of breast cancer in the Canary Islands: a population-based case-control study.

作者信息

García-Segovia Purificación, Sánchez-Villegas Almudena, Doreste Jorge, Santana Francisco, Serra-Majem Lluís

机构信息

Department of Clinical Science, University of Las Palmas of Gran Canaria, Spain.

出版信息

Public Health Nutr. 2006 Feb;9(1A):163-7. doi: 10.1079/phn2005940.

DOI:10.1079/phn2005940

PMID:16512965

Abstract

BACKGROUND

Breast cancer mortality and incidence rates in the Canary Islands, and particularly in Gran Canaria, are higher than those in the rest of Spain.

OBJECTIVES AND DESIGN

A case-control study was designed to assess the role of differential fatty acid intakes and olive oil consumption on breast cancer risk in the Canary Islands. The study was conducted between 1999 and 2001, including a total of 755 women: 291 incident cases with confirmed breast cancer and 464 controls randomly selected from the Canary Island Nutrition Survey (ENCA). A semi-quantitative food-frequency questionnaire was completed and potential confounders were adjusted using unconditional logistic regression.

RESULTS

Compared to the first quintile of intake, the highest quintile of monounsaturated fat intake was significantly related to a lower risk of breast cancer (odds ratio = 0.52; 95% CI 0.30-0.92). Regarding olive oil, the odds ratio for women in the three upper quintiles of consumption (> or =8.8 g/day) was 0.27 (95% CI 0.17-0.42).

CONCLUSION

Our results support the protective role of olive oil consumption on breast cancer among Canaries women.

摘要

背景

加那利群岛，尤其是大加那利岛的乳腺癌死亡率和发病率高于西班牙其他地区。

目的与设计

开展一项病例对照研究，以评估不同脂肪酸摄入量和橄榄油消费对加那利群岛乳腺癌风险的作用。该研究于1999年至2001年间进行，共纳入755名女性：291例确诊为乳腺癌的新发病例以及从加那利岛营养调查（ENCA）中随机选取的464名对照。完成了一份半定量食物频率问卷，并使用无条件逻辑回归对潜在混杂因素进行了调整。