Laohaburanakit P, Hardin K A
Division of Pulmonary and Critical Care Medicine, University of California, Davis, 4150 V Street Suite 3400, Sacramento, CA 95817, USA.
Thorax. 2006 Mar;61(3):267-70. doi: 10.1136/thx.2004.025767.
Primary lymphoma of the lung is rare and is usually of B cell type. Tissue samplings taken by transbronchial biopsy and computed tomographic (CT) guided needle biopsy of the right perihilar area of an elderly woman who presented with refractory pneumonia showed T cell lymphocytosis with no evidence of active infection. The patient's respiratory status rapidly deteriorated and she eventually died. Post mortem examination revealed primary pulmonary T cell lymphoma with natural killer (NK) cell features. We present what may be the first case of primary NK/T cell pulmonary lymphoma and review the literature on the subject.
原发性肺淋巴瘤较为罕见，通常为B细胞型。一名出现难治性肺炎的老年女性患者，经支气管活检及计算机断层扫描（CT）引导下对右肺门周围区域进行穿刺活检获取的组织样本显示T细胞淋巴细胞增多，且无活动性感染迹象。患者的呼吸状况迅速恶化，最终死亡。尸检发现原发性肺T细胞淋巴瘤伴自然杀伤（NK）细胞特征。我们报告了可能为首例原发性NK/T细胞肺淋巴瘤病例，并对该主题的文献进行了综述。
