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青少年和成人紧张型头痛:一项基于33764对双胞胎的人群研究。

Tension-type headache in adolescents and adults: a population based study of 33,764 twins.

作者信息

Russell Michael Bjørn, Levi Niels, Saltyte-Benth Jūrate, Fenger Kirsten

机构信息

Head and Neck Research Group, Akershus University Hospital, 1474, Nordbyhagen, Oslo, Norway. m/

出版信息

Eur J Epidemiol. 2006;21(2):153-60. doi: 10.1007/s10654-005-6031-3.

DOI:10.1007/s10654-005-6031-3
PMID:16518684
Abstract

The aim of this study was to evaluate the 1-year-period prevalence of tension-type headache in a large population based sample. The study population included 33,764 twins aged 12-41 years old from the population based new Danish Twin Registry. They received a posted headache questionnaire and the response rate was 83.5%. The self-reported 1-year-period prevalence of tension-type headache was 86.0%; 78.9% among men and 92.5% among women. The 1-year-period prevalence of infrequent episodic, frequent episodic and chronic tension-type headache was 63.5, 21.6 and 0.9%, respectively. Frequent episodic and chronic tension-type headache was significantly more frequent in women than men. The prevalence of frequent episodic tension-type headache increased slightly in men until age 39 then it declined, while it increased about 20% point in women from age 12 years to age 20-39 years old and then it declined. Congruently, the prevalence of chronic tension-type headache increased until age 39 and declined thereafter in both sexes. Chronic tension-type headache is rare in persons 12-14 years old. These effects were confirmed by age trends of the different subtypes of tension-type headache using a regression model. The prevalence of migraine varied from 7.0 to 16.8% in men and from 8.2 to 31.0% in women. It increased from age 12 to 34 years and then declined. The risk and frequency of tension-type headache was significantly higher in those with migraine than those who had never had migraine. Future large longitudinal follow-up studies are required.

摘要

本研究的目的是评估基于大样本人群的紧张型头痛的1年患病率。研究人群包括来自丹麦新的基于人群的双胞胎登记处的33764名年龄在12 - 41岁的双胞胎。他们收到了一份邮寄的头痛问卷,回复率为83.5%。自我报告的紧张型头痛1年患病率为86.0%;男性为78.9%,女性为92.5%。偶发性、频发性和慢性紧张型头痛的1年患病率分别为63.5%、21.6%和0.9%。频发性和慢性紧张型头痛在女性中比男性更常见。频发性紧张型头痛的患病率在男性中直到39岁略有上升,然后下降,而在女性中从12岁到20 - 39岁上升了约20个百分点,然后下降。同样,慢性紧张型头痛的患病率在39岁之前上升,之后在两性中均下降。慢性紧张型头痛在12 - 14岁的人群中很少见。使用回归模型对紧张型头痛不同亚型的年龄趋势进行分析,证实了上述结果。偏头痛的患病率在男性中为7.0%至16.8%,在女性中为8.2%至31.0%。它从12岁到34岁上升,然后下降。有偏头痛的人患紧张型头痛的风险和频率明显高于从未患过偏头痛的人。需要未来进行大规模的纵向随访研究。

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