Jensen R
The Danish Headache Research Center, Department of Neurology N01, University of Copenhagen, Glostrup Hospital, Denmark.
Cephalalgia. 2003;23 Suppl 1:49-52. doi: 10.1046/j.1468-2982.2003.00574.x.
Despite the tremendous socioeconomic impact of tension-type headache surprisingly little is known about the underlying pathophysiology and treatment. Existing evidence and theories about the relation between central and peripheral mechanisms are discussed. Central sensitization is probably the most important key to understand this widespread disorder. An effective prevention or reversal of this central sensitization will probably be of major importance in future treatment strategies.
尽管紧张型头痛具有巨大的社会经济影响，但令人惊讶的是，人们对其潜在的病理生理学和治疗方法知之甚少。本文讨论了关于中枢和外周机制之间关系的现有证据和理论。中枢敏化可能是理解这种广泛存在的疾病的最重要关键。有效预防或逆转这种中枢敏化可能在未来的治疗策略中至关重要。
