Wong Judy, Wirrell Elaine
University of Alberta, Edmonton, Canada.
Epilepsia. 2006 Mar;47(3):631-9. doi: 10.1111/j.1528-1167.2006.00478.x.
To determine (a) whether children and teens with epilepsy participate in less physical activity and have higher body mass index (BMI) percentiles for age than do their siblings without epilepsy; and (b) what epilepsy-specific factors limit their participation.
Patients 5-17 years, with a >or=3 month history of epilepsy, a development quotient >or=80, no major motor or sensory impairments, and at least one sibling without epilepsy in a similar age range, were identified from the Neurology Clinic database or at the time of clinic visit. Parents completed a questionnaire regarding sedentary activities and group, individual, and total sports activities. Children aged 11-15 years also completed the physical activity portion of the Health Behavior in School Aged Children questionnaire. Clinic charts were reviewed for seizure type, etiology, frequency, duration of epilepsy, and number of antiepileptic drugs (AEDs) ever taken.
Teens with epilepsy participated in fewer group and total sports activities than did controls and were more likely to be potentially overweight or overweight. Receiving three or more AEDs in the past showed a significant negative correlation with sports participation. Although a trend was noted for those with higher seizure frequency to be less active, no other epilepsy-specific factors or prior seizures or seizure-related injury during a sports event correlated with participation in physical activity.
Programs that promote exercise in adolescents with epilepsy should be encouraged to improve their physical, psychological, and social well-being.
确定（a）患有癫痫的儿童和青少年与没有癫痫的兄弟姐妹相比，是否参与的体育活动较少且年龄别体重指数（BMI）百分位数更高；以及（b）哪些癫痫特异性因素限制了他们的参与。
从神经科诊所数据库或在诊所就诊时，识别出年龄在5 - 17岁、有≥3个月癫痫病史、发育商≥80、无重大运动或感觉障碍且至少有一名年龄范围相似的无癫痫兄弟姐妹的患者。父母完成了一份关于久坐活动以及团体、个人和总体体育活动的问卷。11 - 15岁的儿童还完成了《学龄儿童健康行为问卷》中的体育活动部分。查阅临床病历以了解癫痫发作类型、病因、频率、癫痫持续时间以及曾服用的抗癫痫药物（AEDs）数量。
患有癫痫的青少年参与的团体和总体体育活动比对照组少，且更有可能处于潜在超重或超重状态。过去接受三种或更多AEDs与体育活动参与呈显著负相关。尽管注意到癫痫发作频率较高的患者活动较少的趋势，但没有其他癫痫特异性因素或既往癫痫发作或体育赛事中与发作相关的损伤与体育活动参与相关。
应鼓励开展促进癫痫青少年锻炼的项目，以改善他们的身体、心理和社会幸福感。
