慢性给予丙咪嗪可“逆转”B-HT 920诱导的大鼠运动功能减退。
Chronic imipramine "reverses" B-HT 920-induced hypomotility in rats.
作者信息
Serra G, Collu M, D'Aquila P S, De Montis G M, Gessa G L
机构信息
Department of Neuroscience, B.B. Brodie, University of Cagliari, Italy.
出版信息
J Neural Transm Gen Sect. 1991;84(3):237-40. doi: 10.1007/BF01244974.
PMID:1652984
Abstract
B-HT 920, a selective DA autoreceptor agonist, reduced motor activity in rats. Chronic, but not acute, treatment with imipramine (IMI) reversed this effect. The mechanism by which chronic IMI reverses the B-HT 920 effect is discussed.
摘要
B-HT 920，一种选择性多巴胺自身受体激动剂，可降低大鼠的运动活性。慢性而非急性给予丙咪嗪（IMI）可逆转这种效应。本文讨论了慢性IMI逆转B-HT 920效应的机制。
Zotero 插件