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摄入荨麻提取物对大鼠血脂谱的影响。

Effect of Urtica dioica extract intake upon blood lipid profile in the rats.

作者信息

Daher Costantine F, Baroody Karmen G, Baroody George M

机构信息

School of Arts and Sciences, Natural Science Division, Lebanese American University, P.O. Box 36, Byblos, Lebanon.

出版信息

Fitoterapia. 2006 Apr;77(3):183-8. doi: 10.1016/j.fitote.2006.01.010. Epub 2006 Feb 23.

DOI:10.1016/j.fitote.2006.01.010
PMID:16540261
Abstract

Aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of Urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile. Significant decreases in total cholesterol, LDL cholesterol, LDL/HDL cholesterol ratio and plasma total apo B were observed. Assessment of GOT, GPT and LDH activities showed that no liver damage has occurred during the study period.

摘要

将普通饮食或高脂饮食喂养的大鼠给予30天的荨麻水提取物(150毫克/千克/天),以及较少剂量的石油醚提取物(20毫克/千克/天),可改善血脂状况。观察到总胆固醇、低密度脂蛋白胆固醇、低密度脂蛋白/高密度脂蛋白胆固醇比值和血浆总载脂蛋白B显著降低。对谷草转氨酶、谷丙转氨酶和乳酸脱氢酶活性的评估表明,在研究期间未发生肝损伤。

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