Vijaya L, George R, Arvind H, Baskaran M, Raju P, Ramesh S V, Paul P G, Kumaramanickavel G, McCarty C
Vision Research Foundation, Sankara Nethralaya, 18 College Road, Chennai, India 600 006.
Br J Ophthalmol. 2006 Apr;90(4):407-10. doi: 10.1136/bjo.2005.081406.
To study the prevalence and causes of blindness in a rural south Indian population.
3924/4800 enumerated (81.75%) subjects, aged 40 years or more from rural Tamil Nadu, underwent comprehensive ophthalmic examination-visual acuity, refraction, intraocular pressure, gonioscopy, cataract grading (LOCS II), retinal examination, and SITA Standard where indicated. Blindness was defined using WHO criteria as best corrected visual acuity of less than 3/60 and/or visual field of less than 10 degrees in the better eye. The influence of age, sex, literacy, and occupation was assessed using multiple logistic regression.
753 subjects (19.2%; 321 males, 432 females) presented with a visual acuity of <3/60; 132 subjects (3.36%, 95% CI: 2.80 to 3.93) were diagnosed to be blind. Cataract was responsible in 74.62% of eyes; glaucoma, cystoid macular oedema, optic atrophy, and corneal scars accounted for 3.79% each. Bilateral causes of blindness were cataract (78.63%), glaucoma (4.29%), optic atrophy (3.42%), cystoid macular oedema, and corneal scars (2.56% each). In 19 eyes (7.2%) the blindness was probably related to cataract surgery. Blindness was positively associated with increasing age (p<0.0001).
3.36% of the studied rural population was bilaterally blind, with cataract being the single most important cause.
研究印度南部农村人群失明的患病率及病因。
对来自泰米尔纳德邦农村地区40岁及以上的3924名(占应查人数4800名的81.75%)受试者进行全面眼科检查,包括视力、验光、眼压、前房角镜检查、白内障分级(LOCS II)、视网膜检查,并在必要时进行SITA标准检查。失明按照世界卫生组织标准定义为较好眼最佳矫正视力低于3/60和/或视野小于10度。采用多因素logistic回归评估年龄、性别、识字率和职业的影响。
753名受试者(19.2%;男性321名,女性432名)视力<3/60;132名受试者(3.36%,95%可信区间:2.80至3.93)被诊断为失明。白内障导致74.62%的眼失明;青光眼、黄斑囊样水肿、视神经萎缩和角膜瘢痕各占3.79%。失明的双侧病因包括白内障(78.63%)、青光眼(4.29%)、视神经萎缩(3.42%)、黄斑囊样水肿和角膜瘢痕(各2.56%)。19只眼(7.2%)的失明可能与白内障手术有关。失明与年龄增加呈正相关(p<0.0001)。
在所研究的农村人群中,3.36%为双侧失明,白内障是最重要的单一病因。