Herzberg A J, Bossen E H, Walther P J
Department of Pathology, Duke University School of Medicine, Durham, North Carolina 27710.
Cancer. 1991 Sep 1;68(5):1015-20. doi: 10.1002/1097-0142(19910901)68:5<1015::aid-cncr2820680518>3.0.co;2-z.
Adenoid cystic carcinoma (ACC) of the breast is a rare histologic type of breast cancer associated with a good prognosis. A woman who earlier had a pulmonary metastasis surgically resected 6 years postmastectomy developed clinically symptomatic bleeding from a renal metastasis 12 years postmastectomy. An atypical angiographic picture (moderate vascularization) for secondary renal neoplasms was observed. The characteristic histologic features of ACC were present in all specimens; ultrastructural characteristics of ACC were identified in the renal lesion. Successful surgical management of these metachronous solitary metastases demonstrates the therapeutic utility of aggressive management in maintaining disease control of this histologic type of breast cancer.
乳腺腺样囊性癌(ACC)是一种罕见的组织学类型的乳腺癌,预后良好。一名女性在乳房切除术后6年接受了肺转移瘤的手术切除,在乳房切除术后12年出现了有临床症状的肾转移瘤出血。观察到继发性肾肿瘤的非典型血管造影表现(中等血管化)。所有标本均呈现ACC的特征性组织学特征;在肾病变中鉴定出ACC的超微结构特征。对这些异时性孤立转移瘤的成功手术治疗证明了积极治疗在维持这种组织学类型乳腺癌的疾病控制方面的治疗效用。