Coelho-Marques F Z, Wagner M B, Poli de Figueiredo C E, d'Avila D O
Programa de Pós-Graduaçã o em Medicina e Ciências da Saúde (Nefrologia), Faculdade de Medicina/Hospital São Lucas/Instituto de Pesquisas Biomédicas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Int J Impot Res. 2006 Nov-Dec;18(6):539-43. doi: 10.1038/sj.ijir.3901470. Epub 2006 Mar 23.
Patients in end-stage renal disease (ESRD) present reduced quality of life (QOL) and impaired sexual function. Previous studies have mostly addressed male sexual dysfunction. This was a cross-sectional controlled study that applied a general and the World Health Organization Quality of Life-bref questionnaires to assess demographic, marital, and sexual conditions, and QOL in 86 healthy women aged 18 or more years (Group 1), and 38 female ESRD patients on dialysis for at least 2 months (Group 2). The effect of several explanatory variables upon QOL components was estimated. Quality of life was lower in Group 2 -- overall, and on physical and environment domains. To undergo dialysis and to be poorly educated negatively affected the QOL. Yet age, a stable marital relationship or being sexually active had no effect. Female patients undergoing chronic dialysis had lower QOL and were significantly more sexually dysfunctional than comparable healthy women. Decline in sexual function had no effect on the QOL.
终末期肾病（ESRD）患者的生活质量（QOL）下降，性功能受损。以往的研究大多关注男性性功能障碍。这是一项横断面对照研究，应用一般问卷和世界卫生组织生活质量简表来评估86名18岁及以上健康女性（第1组）和38名接受透析至少2个月的女性ESRD患者（第2组）的人口统计学、婚姻和性状况以及生活质量。估计了几个解释变量对生活质量组成部分的影响。第2组的生活质量较低——总体上以及在身体和环境领域。接受透析和受教育程度低对生活质量有负面影响。然而，年龄、稳定的婚姻关系或性活跃并没有影响。接受慢性透析的女性患者生活质量较低，性功能障碍明显多于可比的健康女性。性功能下降对生活质量没有影响。
