Chen Ying, Lin Shou-Qing, Wei Yang, Gao Hong-Lian, Wang Shao-Hai, Wu Zheng-Lai
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, PR China.
Menopause. 2008 Jan-Feb;15(1):144-9. doi: 10.1097/gme.0b013e318115150e.
To assess the impact of menopause, age, and other factors on quality of life (QOL).
Generally healthy women aged 35 to 64 years were recruited from a general community in Beijing, People's Republic of China. An instrument including the Chinese version of the Menopause-Specific Quality of Life Questionnaire was used to obtain data.
A gradual decline of QOL was seen from pre- to peri- and postmenopausal women in the same age group. Statistically impaired QOL was associated with the peri- and postmenopausal women in vasomotor and physical domains but only with the postmenopausal women in psychosocial and sexual domains. Early postmenopausal women presented the worse QOL in vasomotor, psychosocial and physical domains. The gradually declining sexual QOL was related to the advance of menopause. Age had a negative impact on QOL in vasomotor and sexual domains. Women who assessed their own health as common (fair) or weak (poor) reported worse QOL than those who decribed themselves as healthy. Women with a higher body mass index reported more vasomotor symptoms.
Menopause might have a negative impact on QOL independent of age in community-based women in China. There seemed to be a potential model of the relationship of menopause status to change in QOL, but this needs supporting evidence from longitudinal studies. The association of QOL with age and other factors also should be considered.
评估绝经、年龄及其他因素对生活质量(QOL)的影响。
从中华人民共和国北京的一个普通社区招募35至64岁的一般健康女性。使用包括中文版绝经特异性生活质量问卷的工具获取数据。
同一年龄组的绝经前、围绝经期和绝经后女性的生活质量呈逐渐下降趋势。在血管舒缩和身体领域,生活质量在统计学上受损与围绝经期和绝经后女性有关,但在心理社会和性领域仅与绝经后女性有关。绝经后早期女性在血管舒缩、心理社会和身体领域的生活质量最差。性方面生活质量的逐渐下降与绝经进展有关。年龄对血管舒缩和性领域的生活质量有负面影响。将自己的健康状况评估为一般(尚可)或较差(不佳)的女性报告的生活质量比将自己描述为健康的女性更差。体重指数较高的女性报告有更多的血管舒缩症状。
在中国社区女性中,绝经可能对生活质量产生独立于年龄的负面影响。绝经状态与生活质量变化之间似乎存在一种潜在的关系模式,但这需要纵向研究的支持证据。还应考虑生活质量与年龄及其他因素的关联。