1,25-二羟维生素D3受体在鸡法氏囊中的分布
Distribution of the 1,25 dihydroxy-vitamin D3 receptor in the bursa of Fabricius of chicken.
作者信息
Petrini M, Bianchi F, Dolfi A, Lupetti M
机构信息
Chair of Histology and Embryology, Faculty of Medicine, University of Pisa, Italy.
出版信息
Experientia. 1991 Aug 15;47(8):838-41. doi: 10.1007/BF01922468.
The vitamin D3 metabolite 1,25(OH)2D3 is probably involved in B lymphocyte ontogeny. We therefore determined the distribution of the 1,25(OH)2D3 receptor in the bursa of Fabricius and spleen cells of 7-day-old chicks, by immunohistochemistry using a monoclonal antibody against the chick intestinal cell 1,25(OH)2D3 receptor. The bursa cells of young (7-day-old) chicks contained large amounts of receptor while the spleen cells did not. The bursa cells of older (35-day-old) chicks contained fewer receptors, but the number of receptors in the spleen increased.
维生素D3代谢产物1,25(OH)2D3可能参与B淋巴细胞的个体发育。因此，我们使用针对雏鸡肠道细胞1,25(OH)2D3受体的单克隆抗体，通过免疫组织化学方法测定了7日龄雏鸡法氏囊和脾细胞中1,25(OH)2D3受体的分布。幼龄（7日龄）雏鸡的法氏囊细胞含有大量受体，而脾细胞则没有。老龄（35日龄）雏鸡的法氏囊细胞含有的受体较少，但脾中的受体数量增加。
Zotero 插件