乳酸奈瑟菌和脑膜炎奈瑟菌的脱氧核糖核酸部分重关联。
Partial Reassociation Between the Deoxyribonucleic Acids of Neisseria lactamicus and Neisseria meningitidis.
机构信息
Department of Microbiology, Naval Medical Research Institute, Bethesda, Maryland 20014.
出版信息
Infect Immun. 1971 Feb;3(2):274-7. doi: 10.1128/iai.3.2.274-277.1971.
The similarity in polynucleotide sequence of seven strains of Neisseria lactamicus to N. meningitidis and to each other was investigated. The per cent reassociation between single-stranded N. lactamicus deoxyribonucleic acid (DNA), immobilized on membrane filters, with labeled single-stranded DNA fragments derived from strain SD-6 (group C) of N. meningitidis varied from 75 to 56. With strain ATCC 23972 of N. lactamicus furnishing the labeled DNA fragments, reassociation was 72% with N. meningitidis, 31% with N. subflava, and 98 to 72% with the other strains of N. lactamicus. It is concluded that on the basis of DNA reassociation N. lactamicus can be distinguished from N. meningitidis and N. subflava, but constitutes a relatively heterogeneous species.
研究了 7 株乳糖奈瑟菌与脑膜炎奈瑟菌以及彼此之间的多核苷酸序列相似性。固定在膜过滤器上的单链乳糖奈瑟菌脱氧核糖核酸（DNA）与标记的来自脑膜炎奈瑟菌 SD-6（C 群）菌株的单链 DNA 片段的重新杂交率从 75%到 56%不等。用乳糖奈瑟菌 ATCC 23972 提供标记的 DNA 片段，与脑膜炎奈瑟菌的重杂交率为 72%，与副流感奈瑟菌为 31%，与其他乳糖奈瑟菌菌株为 98%至 72%。结论是，根据 DNA 重杂交，乳糖奈瑟菌可以与脑膜炎奈瑟菌和副流感奈瑟菌区分开来，但构成一个相对异质的种。
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