Institut für Medizinische Mikrobiologie, Johannes Gutenberg-University, D-65 Mainz, Germany.
Infect Immun. 1974 Nov;10(5):1105-9. doi: 10.1128/iai.10.5.1105-1109.1974.
Injection of dextran sulfate 500 caused loss of antibacterial resistance. Mice became more susceptible to an infection with Listeria monocytogenes and were unable to develop antilisterial immunity after both active and passive immunization with passively administered spleen cells from Listeria-immune donors. Indirect evidence suggests that the phagocytic component of cell-mediated resistance to bacterial infection is the site of attack of dextran sulfate.
注射硫酸葡聚糖 500 导致抗菌抗性丧失。在经主动和被动免疫接种李斯特菌免疫供体的被动给予脾细胞后,小鼠对李斯特菌感染的易感性增加,并且无法产生抗李斯特菌免疫力。间接证据表明,细胞介导的细菌感染抗性的吞噬成分是硫酸葡聚糖攻击的部位。