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[颅脑创伤急性期单核吞噬细胞的反应性]

[The reactivity of the mononuclear phagocytes in the acute period of craniocerebral trauma].

作者信息

Khil'ko V A, Khlunovskiĭ A N, Gizatullin Sh Kh

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1991 Mar-Apr(2):19-21.

PMID:1656663
Abstract

The article analyses the condition of one of the main links of the defence status--the cells of the mononuclear phagocytotic system in the acute period of craniocerebral trauma (CCT). The authors established the existence of a dependence of the functional condition of the peripheral blood monocytes on the CCT severity. Disorders of the monocyte functional condition (phagocytosis, monocyte test) were most marked in a severe CCT. Early (in the first 24 hours after the trauma) activation of mononuclears develops in such case. Standard nonspecific response of monocytes to traumatic damage is maintained in mild CCT.

摘要

本文分析了防御状态的主要环节之一——颅脑创伤(CCT)急性期单核吞噬细胞系统细胞的状况。作者确定了外周血单核细胞的功能状态与CCT严重程度之间存在相关性。单核细胞功能状态(吞噬作用、单核细胞试验)的紊乱在严重的CCT中最为明显。在这种情况下,会出现单核细胞的早期(创伤后24小时内)激活。在轻度CCT中,单核细胞对创伤损伤的标准非特异性反应得以维持。

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