印度犬细小病毒分离株VP2基因序列分析
Analysis of VP2 gene sequences of canine parvovirus isolates in India.
作者信息
Chinchkar S R, Mohana Subramanian B, Hanumantha Rao N, Rangarajan P N, Thiagarajan D, Srinivasan V A
机构信息
Indian Immunologicals Ltd, Gachibowli (PO), Hyderabad, India.
出版信息
Arch Virol. 2006 Sep;151(9):1881-7. doi: 10.1007/s00705-006-0753-8. Epub 2006 Apr 3.
The epidemiology of canine parvovirus (CPV) infections in dogs in India was examined using 27 isolates collected during a two-year period. The VP2 genes of 22 isolates were sequenced, and the deduced amino acid sequences were compared. The results indicated that the isolates belonged to CPV type 2a except four, which belonged to CPV type 2b. Comparison of the VP2 gene sequences revealed that the Indian isolates formed separate lineages distinct from the South East Asian isolates. The canine parvovirus isolates in India appear to evolve independently, and distinct geographical patterns of evolution could not be discerned in the isolates examined.
利用在两年时间内收集的27株分离株，对印度犬细小病毒（CPV）感染犬的流行病学进行了研究。对22株分离株的VP2基因进行了测序，并对推导的氨基酸序列进行了比较。结果表明，除4株属于CPV 2b型外，其余分离株均属于CPV 2a型。VP2基因序列比较显示，印度分离株形成了与东南亚分离株不同的独立谱系。印度的犬细小病毒分离株似乎是独立进化的，在所检测的分离株中未发现明显的地理进化模式。
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