Willmott F E
Br J Vener Dis. 1975 Apr;51(2):119-22. doi: 10.1136/sti.51.2.119.
A study of 552 female patients was undertaken to determine the frequency of yeast infections in women attending a V.D. clinic. The findings were as follows: (1) 207 of the 552 (37.5 per cent.) were found to have yeasts. (2) C. albicans accounted for 86 per cent. of these yeasts. (3) There was no difference in incidence related to age or seasonal variation. (4) Oral contraceptives increased the incidence of yeasts (43.2 per cent. on "the pill"; 33.2 per cent. not on the pill"), but the incidence of Trichomonas was decreased (6.8 per cent. on "the pill", 19.3 per cent. not on "the pill"). (5) Previous antibiotics also contributed to the incidence; 23.2 per cent. of patients with yeasts had had antibiotics previously compared with 13.6 per cent. of those without yeasts. (6) Other infections were associated in seventy cases (33.8 per cent.). (7) Culture is essential for the detection of yeasts; 64 per cent. were positive only on culture. (8) Symptoms were present in 70 per cent. of patients with yeasts. (9) 93 male consorts were seen and in 31 (33 per cent.) yeasts were detected by smear, or culture. Of the 47 in whom cultures were examined, 23 (49 per cent.) were positive. The general factors affecting the incidence of yeasts are discussed as well as the differentiation of the saprophytic from the pathogenic role of yeasts. It is suggested that asymptomatic yeast infections are often best treated, but that each case should be considered individually. Male consorts should also be treated to prevent re-infection.
对552名女性患者进行了一项研究,以确定在性病诊所就诊的女性中酵母菌感染的发生率。研究结果如下:(1)552名患者中有207名(37.5%)被发现感染了酵母菌。(2)白色念珠菌占这些酵母菌的86%。(3)发病率与年龄或季节变化无关。(4)口服避孕药会增加酵母菌感染的发生率(服用避孕药者为43.2%;未服用避孕药者为33.2%),但滴虫感染的发生率会降低(服用避孕药者为6.8%,未服用避孕药者为19.3%)。(5)先前使用抗生素也与发病率有关;感染酵母菌的患者中有23.2%先前使用过抗生素,而未感染酵母菌的患者中这一比例为13.6%。(6)70例(33.8%)伴有其他感染。(7)培养对于检测酵母菌至关重要;64%的病例仅通过培养呈阳性。(8)70%的酵母菌感染患者有症状。(9)对93名男性配偶进行了检查,其中31名(33%)通过涂片或培养检测出酵母菌。在47名进行培养检查的患者中,23名(49%)呈阳性。文中讨论了影响酵母菌感染发生率的一般因素,以及酵母菌腐生作用与致病作用的区别。建议对于无症状的酵母菌感染通常最好进行治疗,但每个病例都应单独考虑。男性配偶也应接受治疗以防止再次感染。