Li M F, Hirata Y, Xu G J, Niwa M, Wu H M
China Pharmaceutical University, Nanjing.
Yao Xue Xue Bao. 1991;26(4):307-10.
According to IR, UV, MS and NMR spectra of the compounds isolated from the fresh stem of Dendrobium loddigesii Rolfe (a Chinese medicine), 3 constituents were identified. They are shihunidine, shihunine and dendrophenol (4,4'- dihydroxy-3,3',5-trimethoxybibenzyl). Chemical reactions showed that shihunidine was derived from shihunine during isolation. Shihunidine and shihunine were shown to be inhibitors of Na+, K+-ATPase of the rat kidney.
根据从中药石斛新鲜茎中分离出的化合物的红外光谱、紫外光谱、质谱和核磁共振光谱，鉴定出了3种成分。它们是石斛宁定、石斛宁和石斛酚（4,4'-二羟基-3,3',5-三甲氧基联苄）。化学反应表明，在分离过程中石斛宁定是由石斛宁衍生而来。已证明石斛宁定和石斛宁是大鼠肾脏Na +，K + -ATP酶的抑制剂。
