Shienbaum Gary, Tasman William S
Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA.
Retina. 2006 Apr;26(4):422-4. doi: 10.1097/01.iae.0000238545.44132.a2.
To document the recurrent nature of Coats Disease.
This study is a retrospective chart review approved by our Institutional Review Board. Thirteen patients (13 eyes) were diagnosed with Coats Disease starting in 1966. Age, visual acuity, time of onset, method of treatment, and the number and intervals of recurrences were documented. Recurrences were recorded once initial treatment proved successful and most exudates had absorbed. The length of follow-up for each patient and the most recent visual acuity was recorded.
The average follow-up period for the 13 patients was 12.4 years with a range from 4.0 to 37.5 years. Eleven patients (85%) were male, two (15%) were female and all had unilateral involvement. The average age at diagnosis was 7.0 years with a range from 9 months to 27 years. Four out of the twelve treated patients (33%) had recurrences, and three of the four had multiple recurrences. The average elapsed time from successful treatment to the first recurrence was 4.3 years with a range from 3.3 to 5.4 years. The average number of recurrences was 3.3.
Coats Disease can recur so it is important that parents educate any affected children regarding the necessity of follow-up, including throughout their adult years.
记录科茨病的复发性。
本研究是一项经机构审查委员会批准的回顾性病历审查。1966年起,13例患者(13只眼)被诊断为科茨病。记录了年龄、视力、发病时间、治疗方法以及复发次数和间隔时间。一旦初始治疗证明成功且大多数渗出物已吸收,即记录复发情况。记录了每位患者的随访时间和最近的视力。
13例患者的平均随访期为12.4年,范围为4.0至37.5年。11例(85%)为男性,2例(15%)为女性,均为单侧受累。诊断时的平均年龄为7.0岁,范围为9个月至27岁。12例接受治疗的患者中有4例(33%)复发,其中4例中有3例多次复发。从成功治疗到首次复发的平均时间为4.3年,范围为3.3至5.4年。平均复发次数为3.3次。
科茨病会复发,因此父母教育任何受影响的孩子了解随访的必要性非常重要,包括在他们成年后的整个时期。