Gao Ya, Jin Tian-bo, Lai Jiang-hua, Zheng Hai-bo, Li Sheng-bin
The State Key Subject for Forensic Sciences, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 P.R.China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006 Apr;23(2):216-8.
To study the short teadem repeat(STR) genetics structure of a Chinese Yunnan Yi racial group.
Genetic distributions for nine STR loci were determined based on STR gene scan marked by fluorescence.
Sixty-nine alleles and 164 kinds of genotypes were detected and identified from 84 unrelated Yi racial individuals. The corresponding gene and genotype frequencies were in 0.0060-0.5060 or 0.0119-0.4167 respectively. The expected and observed genotype frequencies of nine STR loci were in accordance with the Hardy-Weinberg equilibrium(P>0.05). The statistical analyses of nine STR loci showed that PIC was distributed in 0.5804-0.8777, H was in 0.6507-0.8002, DP was in 0.7976-0.9558, EPP was in 0.5207-0.8386, except TPOX and THO1 loci.
Above research data enrich the Chinese genetic database, and play an important role in Chinese genetic study and in forensic application.
研究中国云南彝族人群的短串联重复序列(STR)遗传结构。
基于荧光标记的STR基因扫描确定9个STR位点的基因分布。
从84名无血缘关系的彝族个体中检测并鉴定出69个等位基因和164种基因型。相应的基因频率和基因型频率分别在0.0060 - 0.5060和0.0119 - 0.4167之间。9个STR位点的预期基因型频率和观察到的基因型频率符合哈迪 - 温伯格平衡(P>0.05)。对9个STR位点的统计分析表明,除TPOX和THO1位点外,PIC分布在0.5804 - 0.8777,H在0.6507 - 0.8002,DP在0.7976 - 0.9558,EPP在0.5207 - 0.8386。
上述研究数据丰富了中国遗传数据库,在中国遗传学研究和法医学应用中发挥重要作用。