Joniau Steven, Vander Eeckt Kathy, Van Poppel Hein
Department of Urology, University Hospital Gasthuisberg, Leuven, Belgium.
Nat Clin Pract Urol. 2006 Apr;3(4):198-205. doi: 10.1038/ncpuro0458.
Partial nephrectomy is performed more frequently for small, incidentally discovered, low-stage renal tumors. Importantly, one should distinguish the imperative indications for such surgery from the relative and elective indications, while taking contraindications to nephron-sparing surgery into account. The main advantage of partial nephrectomy over radical nephrectomy is the avoidance of renal insufficiency; the major disadvantages include the possibility of local recurrence and perioperative complications. In this article, the literature on nephron-sparing surgery was reviewed in order to put the management of renal cancer into a modern perspective.
对于偶然发现的小的、低分期肾肿瘤,部分肾切除术的实施更为频繁。重要的是,在考虑保留肾单位手术的禁忌证时,应将此类手术的绝对适应证与相对适应证和选择性适应证区分开来。部分肾切除术相对于根治性肾切除术的主要优点是避免肾功能不全;主要缺点包括局部复发和围手术期并发症的可能性。在本文中,对保留肾单位手术的文献进行了综述,以便从现代角度阐述肾癌的治疗。