Cummins Deborah L, Cummins Jordan M, Pantle Hardin, Silverman Michael A, Leonard Aimee L, Chanmugam Arjun
Department of Dermatology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Mayo Clin Proc. 2006 Apr;81(4):500-7. doi: 10.4065/81.4.500.
Skin cancer has become the most common neoplasm in the United States. With early diagnosis and appropriate management, most skin cancers have an overall 5-year survival rate of 95%. Cutaneous malignant melanoma (CMM), however, has a significantly higher morbidity and mortality, resulting in 65% of all skin cancer deaths. Although the long-term survival rate for patients with metastatic melanoma is only 5%, early detection of CMM carries an excellent prognosis, with surgical excision often being curative. Primary care physicians can play a critical role in reducing morbidity and mortality from CMM by recognizing patients at risk, encouraging the adoption of risk-reducing behaviors, and becoming adept at identifying suspicious lesions.
皮肤癌已成为美国最常见的肿瘤。通过早期诊断和适当治疗,大多数皮肤癌的总体5年生存率为95%。然而,皮肤恶性黑色素瘤(CMM)的发病率和死亡率显著更高,占所有皮肤癌死亡病例的65%。尽管转移性黑色素瘤患者的长期生存率仅为5%,但早期发现CMM预后良好,手术切除通常可治愈。初级保健医生可通过识别高危患者、鼓励采取降低风险行为以及熟练识别可疑病变,在降低CMM的发病率和死亡率方面发挥关键作用。