Nusselder Wilma J, Peeters Anna
Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Netherlands.
J Epidemiol Community Health. 2006 May;60(5):448-55. doi: 10.1136/jech.2005.041558.
Current research of risk factors potentially associated with successful aging faces the difficulty of taking into consideration two distinct outcome measures: survival and functioning. Previous studies either used successful aging measures restricted to survivors or presented more than one outcome measure to handle the dual outcome. This article illustrates the utility of health expectancy measures, based on life tables, to integrate the effects of survival and functioning across all ages. It is shown that three hypothetical successful aging strategies, considered equally successful according to the traditional measures restricted to survivors, are associated with vastly different changes in the years lived with and without disability. Furthermore, the intervention considered most successful when considering multiple successful aging measures, was associated with the largest increase in the time lived with disability. It is recommended that research on successful aging should be based on summary measures of population health that reflect both survival and functioning throughout life. These will provide more relevant information than is currently available for individuals and societies to evaluate and choose between successful aging strategies.
当前对可能与成功老龄化相关的风险因素的研究面临着一个难题，即难以同时考虑两种不同的结果衡量标准：生存和功能。以往的研究要么使用仅限于幸存者的成功老龄化衡量标准，要么提出不止一种结果衡量标准来处理双重结果。本文阐述了基于生命表的健康期望衡量标准在整合所有年龄段生存和功能影响方面的效用。结果表明，根据仅限于幸存者的传统衡量标准被认为同样成功的三种假设性成功老龄化策略，与有残疾和无残疾生存年数的巨大差异相关。此外，在考虑多种成功老龄化衡量标准时被认为最成功的干预措施，与有残疾生存时间的最大增加相关。建议对成功老龄化的研究应基于反映一生生存和功能的人群健康综合衡量标准。这些衡量标准将为个人和社会评估和选择成功老龄化策略提供比目前可用信息更相关的信息。
