德国女性脐带血血清、母血血清和初乳中针对七种轮状病毒血清型的抗体。
Antibodies to seven rotavirus serotypes in cord sera, maternal sera, and colostrum of German women.
作者信息
Brüssow H, Sidoti J, Lerner L, Rahim H, Eckstein W, Werchau H, Mietens C
机构信息
Nestlé Research Centre, Nestec Ltd., Lausanne, Switzerland.
出版信息
J Clin Microbiol. 1991 Dec;29(12):2856-9. doi: 10.1128/jcm.29.12.2856-2859.1991.
Abstract
Forty percent of colostrum samples from German women showed neutralizing antibody titers of greater than or equal to 50 to rotavirus (RV) serotypes 1, 3, 4, and 6. Antibody to serotypes 2, 8, and 9 was less prevalent. Titers are, however, too low to indicate an important effect of colostrum on the RV vaccine take rate. On the other hand, about 50% of the cord serum samples showed high neutralizing-antibody titers to serotypes 1, 3, and 4, which could interfere with the take rate of RV vaccines based on these serotypes in very young infants.
摘要
德国女性初乳样本中，40%对轮状病毒（RV）1、3、4和6型的中和抗体滴度大于或等于50。对2、8和9型的抗体则不太常见。然而，滴度过低，无法表明初乳对RV疫苗接种率有重要影响。另一方面，约50%的脐带血清样本对1、3和4型显示出高中和抗体滴度，这可能会干扰基于这些血清型的RV疫苗在非常年幼婴儿中的接种率。
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