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有或无近视性黄斑病变的高度近视患者的视觉预后:一项10年随访研究。

Visual outcomes for high myopic patients with or without myopic maculopathy: a 10 year follow up study.

作者信息

Shih Y-F, Ho T-C, Hsiao C K, Lin L L-K

机构信息

Department of Ophthalmology, College of Medicine, National Taiwan University Hospital, Taipei.

出版信息

Br J Ophthalmol. 2006 May;90(5):546-50. doi: 10.1136/bjo.2005.081992.

Abstract

AIM

To evaluate the visual outcomes for high myopic patients aged 40 years and older with or without myopic maculopathy.

METHODS

552 high myopic (spherical equivalent < or =-6.0D or axial length > or =26.5 mm) patients were enrolled in the study, 230 cases with myopic maculopathy (at least lacquer cracks were identified) and 322 cases without maculopathy. The initial and final visual acuity (VA) (after 10 years) was compared between two groups. Additionally, the relation between sex, age, refraction, and axial length was analysed to find out the possible risk factors associated with visual outcome in myopic maculopathy.

RESULTS

In 92% of patients aged 40-49, final VA was better than 20/40 after 10 years of follow up. However, it was less than 40% in those older than 60 years. For more than 50% of patients older than 40 years of age with maculopathy, their vision had decreased more than two lines in Snellen VA after 10 years of follow up, compared to only 4.3% of analogues without myopic maculopathy. Patchy atrophy and choroidal neovascularisation in myopic macular degeneration groups showed poorer visual outcome than lacquer cracks in the macular lesion group. Other prognostic factors of visual outcomes were myopic refraction, axial length, and ageing.

CONCLUSIONS

Clearly, prognosis for patients with maculopathy is poorer than for those without maculopathy. Refractive status, axial length, and ageing are the main factors involved in determining the visual outcomes. The macular grading also affects the visual outcome for high myopic patients.

摘要

目的

评估年龄在40岁及以上的高度近视患者有无近视性黄斑病变的视力预后。

方法

552例高度近视(等效球镜度≤-6.0D或眼轴长度≥26.5mm)患者纳入研究,其中230例有近视性黄斑病变(至少发现漆裂纹),322例无黄斑病变。比较两组患者的初始和最终视力(10年后)。此外,分析性别、年龄、屈光不正和眼轴长度之间的关系,以找出与近视性黄斑病变视力预后相关的可能危险因素。

结果

在40 - 49岁的患者中,92%在随访10年后最终视力优于20/40。然而,在60岁以上的患者中这一比例不到40%。在40岁以上患有黄斑病变的患者中,超过50%在随访10年后其斯内伦视力表视力下降超过两行,而在无近视性黄斑病变的类似患者中这一比例仅为4.3%。近视性黄斑变性组的斑片状萎缩和脉络膜新生血管形成的视力预后比黄斑病变组的漆裂纹更差。视力预后的其他预测因素包括近视屈光不正、眼轴长度和年龄。

结论

显然,患有黄斑病变的患者预后比无黄斑病变的患者更差。屈光状态、眼轴长度和年龄是决定视力预后的主要因素。黄斑分级也影响高度近视患者的视力预后。

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