Ostir Glenn V, Goodwin James S
Sealy Center on Aging, University of Texas Medical Branch at Galveston (UTMB), 301 University Boulevard, Galveston, TX 77555-0460, USA.
J Clin Epidemiol. 2006 May;59(5):534-40. doi: 10.1016/j.jclinepi.2005.10.008. Epub 2006 Jan 23.
The health consequences of anxiety in late life have not been adequately investigated. We sought to examine the association between anxiety and death in an older tri-ethnic population.
A longitudinal population-based study of 506 older noninstitutionalized non-Hispanic Whites, non-Hispanic Blacks, and Hispanics aged 75 years or older from Galveston County.
Average age was 80.8 (SD 4.4) and 50.8% were women. Older non-Hispanic Whites (21.6%) reported the highest prevalence of anxiety, followed by Hispanics (12.4%) and non-Hispanic blacks (11.3%) (P=.0001). High anxiety was significantly associated with an increased hazard of all cause death (HR 1.52; 95% CI 1.02, 2.28) and cardiovascular death (HR 1.90; 95% CI 1.06, 3.36); and was associated with an increased hazard of cancer death (HR 2.38; 95% CI 0.88, 6.45) during 5-years of follow-up.
There is a high prevalence of anxiety in late life. Our results indicate an association between anxiety and increased risk of death in persons aged 75 and older.
老年期焦虑对健康的影响尚未得到充分研究。我们试图在一个老年三重种族人群中研究焦虑与死亡之间的关联。
对加尔维斯顿县506名75岁及以上的非机构化非西班牙裔白人、非西班牙裔黑人及西班牙裔老年人进行基于人群的纵向研究。
平均年龄为80.8岁（标准差4.4），女性占50.8%。老年非西班牙裔白人（21.6%）报告的焦虑患病率最高，其次是西班牙裔（12.4%）和非西班牙裔黑人（11.3%）（P = 0.0001）。在5年随访期间，高度焦虑与全因死亡风险增加显著相关（风险比1.52；95%置信区间1.02, 2.28）以及心血管死亡风险增加相关（风险比1.90；95%置信区间1.06, 3.36）；并且与癌症死亡风险增加相关（风险比2.38；95%置信区间0.88, 6.45）。
老年期焦虑患病率较高。我们的结果表明，75岁及以上人群中焦虑与死亡风险增加之间存在关联。
