Pooran Nakechand, Lee David, Sideridis Kostas
Division of Gastroenterology, Long Island Jewish Medical Center, New Hyde Park, New York, NY 11040, USA.
J Clin Gastroenterol. 2006 Mar;40(3):183-5. doi: 10.1097/00004836-200603000-00002.
Hiccups although a common annoyance of life, have been linked with significant morbidity and even death. There are numerous causes of prolonged hiccups, including diseases of the gastrointestinal tract. Hiccups are reported to represent an atypical manifestation of gastroesophageal reflux disease.
We report 4 cases of prolonged hiccups in patients who failed to respond to initial treatment with abortive neurologic medications and who subsequently improved on proton-pump inhibitors. Endoscopic examination revealed severe reflux esophagitis.
Hiccups are an atypical manifestation and may represent a more severe course of gastroesophageal reflux disease.
呃逆虽是生活中常见的困扰，但却与严重发病甚至死亡相关。持续性呃逆有多种病因，包括胃肠道疾病。据报道，呃逆是胃食管反流病的一种非典型表现。
我们报告4例持续性呃逆患者，他们对初始的神经抑制药物治疗无效，随后使用质子泵抑制剂后病情改善。内镜检查显示为严重反流性食管炎。
呃逆是非典型表现，可能代表胃食管反流病更严重的病程。
