Tamai M, Tanimura H, Yamaue H, Tsunoda T, Iwahasi M, Nakai T, Sugimoto Y, Asae M, Sasaki M, Aoki Y
Department of Gastroenterological Surgery, Wakayama Medical College, Japan.
Nihon Geka Hokan. 1991 May 1;60(3):195-202.
We report a case of cholangiocarcinoma presented with bile peritonitis, in which endoscopic nasobiliary drainage (ENBD) as well as pleural and abdominal drainages improved the general condition leading to a radical operation. The case was a 79-year-old woman with the chief complaints of fever and right hypochondralgia due to pleural effusion and infected ascites contaminated with bile including E. coli. However gall-stones were not recognized in any biliary trees. US-guided drainage was performed into the pleural and abdominal cavities because of poor condition. After continuous drainages, peritonitis was improved, but hematoemesis and tarry stool appeared. Emergent endoscopy revealed a multiple gastric ulcer, and the bleeding was stopped by an injection of ethanol. ERCP findings revealed a cholangiocarcinoma in superior and middle portion of the bile duct obstructed nearly completely. After improvement in general condition by ENBD, cholecystectomy, resection of extrahepatic bile duct and subtotal gastrectomy were performed followed the reconstruction with Roux-en-Y method. Postoperative course was uneventful and the patient was discharged at the postoperative 35th day. Thus, the appropriate and opportune multiple biliary drainages can save a patient with cholangiocarcinoma in poor condition and lead to tolerate the operation even if he or she is suffering from severe bile peritonitis.
我们报告一例表现为胆汁性腹膜炎的胆管癌病例,其中内镜下鼻胆管引流(ENBD)以及胸腔和腹腔引流改善了患者的一般状况,从而得以进行根治性手术。该病例为一名79岁女性,主要症状为发热和右季肋部疼痛,伴有胸腔积液以及被包括大肠杆菌在内的胆汁污染的感染性腹水。然而,在任何胆管中均未发现胆结石。由于患者状况不佳,遂在超声引导下对胸腔和腹腔进行引流。持续引流后,腹膜炎有所改善,但出现了呕血和柏油样便。急诊内镜检查发现多处胃溃疡,通过注射乙醇止血。内镜逆行胰胆管造影(ERCP)结果显示胆管中上段胆管癌,几乎完全梗阻。通过ENBD改善一般状况后,进行了胆囊切除术、肝外胆管切除术和胃大部切除术,随后采用Roux-en-Y法进行重建。术后病程顺利,患者于术后第35天出院。因此,恰当且及时的多途径胆管引流可挽救病情较差的胆管癌患者,使其能够耐受手术,即便患者患有严重的胆汁性腹膜炎。