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皮下注射无菌水用于分娩镇痛:一项随机对照试验。

Subcutaneous sterile water injection for labour pain: a randomised controlled trial.

作者信息

Bahasadri Shohreh, Ahmadi-Abhari Sara, Dehghani-Nik Mojghan, Habibi Gholam Reza

机构信息

Department of Gynaecology and Obstetrics, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Aust N Z J Obstet Gynaecol. 2006 Apr;46(2):102-6. doi: 10.1111/j.1479-828X.2006.00536.x.

Abstract

BACKGROUND

About 30% of women experience severe continuous low-back pain in labour, but limited options are available to reduce this pain especially in developing countries and remote areas.

AIMS

To evaluate the efficacy of subcutaneous sterile water injection in reduction of labour pain compared with placebo.

METHODS

One hundred (100) consecutive patients were enrolled in a double-blind randomised controlled trial. During the first stage of labour with planned normal vaginal delivery, the intervention group (n = 50) received 0.5 mL sterile water injected subcutaneously and the control group (n = 50) received normal saline as a placebo. Pain score was measured before and 10 and 45 min after the injection, using the faces rating scale.

MAIN OUTCOME MEASURE

Low-back labour pain.

RESULTS

The two groups were not significantly different regarding maternal age and weight, gestational age, parity and gravidity and degree of effacement. The median pain score was equal in both groups prior to the injection. Pain severity was reduced in both groups after the injection. However, the median pain score in the sterile water group was significantly lower than the placebo group 10 min (P < 0.01), as well as 45 min, after the injection (P < 0.01).

CONCLUSION

Administering one subcutaneous injection of sterile water in a painful point of the lumbosacral area is effective in reducing low-back pain during labour.

摘要

背景

约30%的女性在分娩时会经历严重的持续性下背部疼痛,但减少这种疼痛的选择有限,尤其是在发展中国家和偏远地区。

目的

评估皮下注射无菌水与安慰剂相比在减轻分娩疼痛方面的疗效。

方法

100例连续患者被纳入一项双盲随机对照试验。在计划正常阴道分娩的第一产程中,干预组(n = 50)皮下注射0.5 mL无菌水,对照组(n = 50)接受生理盐水作为安慰剂。使用面部表情评分量表在注射前、注射后10分钟和45分钟测量疼痛评分。

主要观察指标

下背部分娩疼痛。

结果

两组在产妇年龄、体重、孕周、产次、妊娠次数和宫颈消退程度方面无显著差异。注射前两组的中位疼痛评分相等。注射后两组的疼痛严重程度均降低。然而,无菌水组的中位疼痛评分在注射后10分钟(P < 0.01)和45分钟(P < 0.01)时均显著低于安慰剂组。

结论

在腰骶部疼痛点皮下注射一次无菌水可有效减轻分娩期间的下背部疼痛。

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