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皮下及皮内注射无菌水和生理盐水对未生育女性疼痛强度的影响:一项随机对照试验。

The Effect of Subcutaneous and Intracutaneous Injections of Sterile Water and Normal Saline on Pain Intensity in Nulliparous Women: A Randomized Controlled Trial.

作者信息

Rezaie Mehri, Shaabani Sanaz, Jahromi Farzin Sabouri, Jahromi Maryam Efafat, Dakhesh Sheida

机构信息

Nursing and Midwifery Care Research Center, Faculty of Nursing and Midwifery, Jahrom University of Medical Sciences, Jahrom, Iran.

Department of Anaesthesiology and Critical Care and Pain Medicine, Shahid Modarres Hospital, Saveh University of Medical Sciences, Saveh, Iran.

出版信息

Iran J Nurs Midwifery Res. 2019 Sep-Oct;24(5):365-371. doi: 10.4103/ijnmr.IJNMR_87_18.

Abstract

BACKGROUND

Normal vaginal delivery is considered a painful process and it is difficult to tolerate the pain. The goal of this study was to compare the effect of injection of sterile distilled water and normal saline on pain intensity in nulliparous women.

MATERIALS AND METHODS

This triple-blind clinical trial was conducted on 164 nulliparous women randomly selected from among those who were hospitalized in Motahari Hospital of Jahrom, Iran, from 1 May 2012 to 1 October 2013. Women with a gestational age of 37-42 weeks, dilatation of 4-6 cm, and delivery 180 min after the intervention were selected. The subjects were randomly allocated to four groups of intracutaneous and subcutaneous sterile water and normal saline injections. Pain severity was measured 5 min before the injection and every 30 min up to 3 h after the injection using a visual analog scale. The data were analyzed using Chi-square, Scheffe, and Spearman's correlation tests in SPSS software.

RESULTS

There was no significant difference among the four studied groups concerning gestational age and other demographic characteristics. Chi-square test showed lower pain intensity 120 min after the injection in group 4 (subcutaneous injection of normal saline) ( = 14.75, < 0.001) and 150 min after the injection in group 3 (intracutaneous injection of normal saline) ( = 14.75, < 0.001). Chi-square test showed that the duration of the second stage of labor was shorter in group 4 participants (subcutaneous injection of normal saline) ( = -12.23, < 0.001).

CONCLUSIONS

The study showed that subcutaneous and intracutaneous injection of normal saline reduced the intensity of pain during childbirth.

摘要

背景

正常阴道分娩被认为是一个痛苦的过程,疼痛难以忍受。本研究的目的是比较注射无菌蒸馏水和生理盐水对未生育女性疼痛强度的影响。

材料与方法

本三盲临床试验对2012年5月1日至2013年10月1日在伊朗贾赫罗姆莫塔哈里医院住院的164名未生育女性进行。选取孕周为37-42周、宫口扩张4-6厘米且干预后180分钟分娩的女性。受试者被随机分为四组,分别进行皮内和皮下注射无菌水及生理盐水。在注射前5分钟以及注射后每30分钟直至3小时,使用视觉模拟量表测量疼痛严重程度。数据在SPSS软件中使用卡方检验、谢费检验和斯皮尔曼相关性检验进行分析。

结果

四组研究对象在孕周和其他人口统计学特征方面无显著差异。卡方检验显示,第4组(皮下注射生理盐水)在注射后120分钟时疼痛强度较低( = 14.75, < 0.001),第3组(皮内注射生理盐水)在注射后150分钟时疼痛强度较低( = 14.75, < 0.001)。卡方检验表明,第4组参与者(皮下注射生理盐水)第二产程持续时间较短( = -12.23, < 0.001)。

结论

该研究表明,皮下和皮内注射生理盐水可减轻分娩时的疼痛强度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb1/6714122/9a5d895f4cf6/IJNMR-24-365-g001.jpg

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