Chapman Glyn, Hansen Kristian S, Jelsma Jennifer, Ndhlovu Chiratidzo, Piotti Bruno, Byskov Jens, Vos Theo
Department of Obstetrics and Gynaecology, School of Medicine, University of Aberdeen, Aberdeen, UK.
Trop Med Int Health. 2006 May;11(5):660-71. doi: 10.1111/j.1365-3156.2006.01601.x.
To rank health problems contributing most to the burden of disease in Zimbabwe using disability-adjusted life years as the population health measure.
Epidemiological information was derived from multiple sources. Population size and total number of deaths by age and sex for the year 1997 were taken from a nationwide census. The cause of death pattern was determined based on data from the Vital Registration System, which was adjusted for under-reporting of human immunodeficiency virus (HIV) and reallocation of ill-defined causes. Non-fatal disease figures were estimated based on local disease registers, surveys and routine health service data supplemented by estimates from epidemiological studies from other settings if no Zimbabwean sources were available. Disease and public health experts were consulted about the identification of the best possible sources of information, the quality of these sources and data adjustments made.
From the information collected, HIV infection emerged as the single most serious public health problem in Zimbabwe responsible for 49% of the total disease burden. A quarter of the total burden of disease was attributed to morbidity rather than premature mortality. The share of the disease burden was similar in females and males.
Using local sources of information to a large extent, it was possible to develop plausible estimates of the size and the relative significance of the major health problems in Zimbabwe. The disease pattern of Zimbabwe differed substantially from regional estimates for sub-Saharan Africa justifying the need for countries to develop their own burden of disease estimates.
以伤残调整生命年作为人群健康衡量指标,对津巴布韦造成疾病负担最大的健康问题进行排序。
流行病学信息来源于多个渠道。1997年按年龄和性别的人口规模及死亡总数取自全国人口普查。死亡原因模式根据生命登记系统的数据确定,该数据针对人类免疫缺陷病毒(HIV)报告不足及不明原因重新分配进行了调整。非致命疾病数据根据当地疾病登记、调查和常规卫生服务数据估算,若没有津巴布韦的相关数据,则辅以其他地区流行病学研究的估算。就最佳信息来源的确定、这些来源的质量以及所做的数据调整,咨询了疾病和公共卫生专家。
从收集到的信息来看,HIV感染成为津巴布韦最严重的单一公共卫生问题,占疾病总负担的49%。疾病总负担的四分之一归因于发病而非过早死亡。疾病负担在女性和男性中的占比相似。
在很大程度上利用当地信息来源,有可能对津巴布韦主要健康问题的规模和相对重要性做出合理估计。津巴布韦的疾病模式与撒哈拉以南非洲地区的估计有很大不同,这证明各国需要制定自己的疾病负担估计数。