Epidemiology & Disease Control Division, Ministry of Health, College of Medicine Building, 16 College Road, Singapore.
Singapore Med J. 2009 May;50(5):468-78.
The Singapore Burden of Disease (SBoD) Study 2004 provides a comprehensive and detailed assessment of the size and distribution of health problems in Singapore. It is the first local study to use disability-adjusted life years (DALYs) to quantify the total disease burden.
The SBoD study applied the methods developed for the original Global Burden of Disease study to data specific to Singapore to compute the DALYs. DALY is a summary measure of population health that combines time lost due to premature mortality (years of life lost [YLL]) with time spent in ill-health (broadly-termed disability) arising from incident cases of disease or injury (years of life lost due to disability [YLD]). DALYs, stratified by gender and age group, were calculated for more than 130 specific health conditions for the Singapore resident population for the year 2004.
In 2004, diabetes mellitus, ischaemic heart disease and stroke were the top three leading causes of premature death and ill-health in Singapore, and together accounted for more than one-quarter (28 percent) of the total disease burden (in DALYs). Morbidity burden (YLD) was responsible for 52 percent of the total DALYs, with diabetes mellitus, anxiety and depression, and Alzheimer's disease and other dementias being the main sources of the total YLDs. Ischaemic heart disease, stroke and lung cancer were the major contributors to the premature mortality burden (YLL).
This study provides an objective and systematic assessment of the fatal and nonfatal health conditions in Singapore to support priority setting in public health policies and research.
2004 年新加坡疾病负担研究提供了对新加坡健康问题的规模和分布的全面而详细的评估。这是首次使用残疾调整生命年(DALY)来量化总疾病负担的本地研究。
新加坡疾病负担研究采用了最初全球疾病负担研究开发的方法,针对新加坡特定的数据来计算 DALY。DALY 是一种综合衡量人口健康的指标,它结合了因过早死亡而损失的时间(生命损失年 [YLL])和因疾病或损伤导致的患病时间(广义上称为残疾)(因残疾而损失的生命年 [YLD])。对 2004 年新加坡居民人口的 130 多种特定健康状况进行了按性别和年龄组分层的 DALY 计算。
2004 年,糖尿病、缺血性心脏病和中风是新加坡导致过早死亡和患病的前三大主要原因,它们共同占总疾病负担(DALYs)的四分之一以上(28%)。疾病负担(YLD)占总 DALYs 的 52%,其中糖尿病、焦虑和抑郁以及阿尔茨海默病和其他痴呆症是总 YLD 的主要来源。缺血性心脏病、中风和肺癌是导致过早死亡负担(YLL)的主要因素。
这项研究提供了对新加坡致命和非致命健康状况的客观和系统评估,以支持公共卫生政策和研究中的优先事项制定。