[闭合性颅脑创伤后病程进展中的免疫因素]

[Immunologic component in the pathogenesis of a progressive course following closed cranio-cerebral trauma].

作者信息

Gorbunov V I, Likhterman L B, Gannushkina I V

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(6):65-70.

Abstract

Overall 393 patients with different types of closed brain injury (CBI) were examined for the immunological blood parameters in the acute and late periods. The decrease of immunological defence of the organism and possibilities of inflammatory complications in the lungs were established. CBI was found to run a progredient course in 27.7% of patients who suffered brain concussions++, in 54.5% of cases after repeated mild CBI, and in 73.7% of patients after severe CBI and CBI of medium gravity. Some immunological criteria and an approximate scale of a probability of the progredient course of CBI were proposed.

摘要

对393例不同类型的闭合性脑损伤（CBI）患者在急性期和后期进行了血液免疫学参数检查。发现机体免疫防御功能下降以及肺部发生炎症并发症的可能性。结果显示，在脑震荡++的患者中，27.7%的CBI呈进行性发展；在反复轻度CBI后的病例中，54.5%呈进行性发展；在重度CBI和中度重力CBI后的患者中，73.7%呈进行性发展。提出了一些免疫学标准以及CBI进行性发展过程的概率大致量表。