Antokhin A I, Popova N Ia, Gembitskiĭ D S, Romanov Iu A
Biull Eksp Biol Med. 1991 Jul;112(7):98-9.
Chalone-containing preparation from ascite Ehrlich's tumour blocks these cell transition from G2-phase to mitosis and its motion in mitosis in vitro (G2-block, M-block). Adrenaline blocks these cell transition from G2-phase to mitosis. Propranolol raises G2-block of chalone or adrenaline. Consequently this way of chalones action on cell division includes beta-adrenergic receptors influence of preparation on cell motion in mitosis doesn't change with addition of propranolol. Consequently this way of chalone system action on mitosis doesn't include beta-adrenergic receptors.
来自艾氏腹水瘤的含抑素制剂可阻止这些细胞从G2期过渡到有丝分裂,并阻止其在体外有丝分裂中的运动(G2期阻滞、M期阻滞)。肾上腺素可阻止这些细胞从G2期过渡到有丝分裂。普萘洛尔可增强抑素或肾上腺素的G2期阻滞作用。因此,抑素对细胞分裂的作用方式包括β-肾上腺素能受体的影响,制剂对有丝分裂中细胞运动的影响不会因加入普萘洛尔而改变。因此,抑素系统对有丝分裂的作用方式不包括β-肾上腺素能受体。