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[使用高压色谱法从艾氏腹水瘤中分离含查耳酮的物质]

[Fractionation of a chalone-containing substance from Ehrlich's ascites tumor using high pressure chromatography].

作者信息

Popova N Ia, Antokhin A I, Adrianov N V, Tret'iakova L Z, Romanov Iu A

出版信息

Biull Eksp Biol Med. 1991 Oct;112(10):418-9.

PMID:1839508
Abstract

The effect of various fractions of chalone--containing preparation from ascyte Ehrlich's tumour obtained by high performance liquid chromatography (HPLC) on mitotic activity and DNA synthesis in the tumour has been studied. After filtration the division of active chalone component which inhibits entering cells into M-phase and S-phase took place. The component inhibiting DNA synthesis eluated with G1-chalone.

摘要

研究了通过高效液相色谱法（HPLC）从艾氏腹水瘤细胞中获得的含查隆的制剂的不同组分对肿瘤有丝分裂活性和DNA合成的影响。过滤后，发生了抑制细胞进入M期和S期的活性查隆成分的分离。抑制DNA合成的成分与G1-查隆一起洗脱出来。

相似文献

1
[Fractionation of a chalone-containing substance from Ehrlich's ascites tumor using high pressure chromatography].[使用高压色谱法从艾氏腹水瘤中分离含查耳酮的物质]
Biull Eksp Biol Med. 1991 Oct;112(10):418-9.
2
[Effect of different fractions obtained by gel filtration of a chalone-containing preparation from Ehrlich ascites tumor on mitotic activity and DNA synthesis in this tumor].[从艾氏腹水瘤含查隆的制剂经凝胶过滤得到的不同级分对该肿瘤有丝分裂活性和DNA合成的影响]
Biull Eksp Biol Med. 1988 Aug;106(8):202-4.
3
[Effect of a chalone-containing preparation from Ehrlich ascites tumor on DNA synthesis and cell division in the tumor in relation to the time of day].
Tsitologiia. 1982 Nov;24(11):1312-8.
4
[Effect of different doses of a chalone-containing alcohol precipitate of Ehrlich ascitic tumor on the mitotic activity and DNA synthesis in this tumor].[不同剂量艾氏腹水瘤含抑素乙醇沉淀物对该肿瘤有丝分裂活性及DNA合成的影响]
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[Determination of the biological activity of chalone-containing preparation of Ehrlich ascites carcinoma and its fractions, prepared using high performance liquid chromatography, in a culture of cells of this tumor].[利用高效液相色谱法制备的艾氏腹水癌含抑素制剂及其组分在该肿瘤细胞培养物中的生物活性测定]
Biull Eksp Biol Med. 1994 Jan;117(1):80-2.
6
[Action of the chalone from Ehrlich's ascites, tumor in mice on the mitotic activity in this tumor after single and double administrations].[艾氏腹水瘤抑素对小鼠该肿瘤单次及两次给药后有丝分裂活性的作用]
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[Effects of propranolol on mitosis-inhibiting activity of G2-chalone and adrenaline in cell culture of Ehrlich's ascites tumor].[普萘洛尔对艾氏腹水瘤细胞培养中G2期抑素和肾上腺素的有丝分裂抑制活性的影响]
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8
[Relation between the mitosis-inhibitory activity of a chalone preparation of Ehrlich ascites tumor and its diurnal secretion].[艾氏腹水瘤查隆制剂的有丝分裂抑制活性与其昼夜分泌之间的关系]
Biull Eksp Biol Med. 1981 Mar;91(3):343-5.
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[Cell division and changes of the duration of mitosis in murine Ehrlich ascites carcinoma after a single administration of chalone-containing extract from this tumor].[单次给予含抑素的小鼠艾氏腹水癌提取物后该肿瘤的细胞分裂及有丝分裂持续时间的变化]
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[Effect of adrenaline on the mitosis-inhibiting action of a chalone-containing preparation in Ehrlich ascites tumor].[肾上腺素对含抑素制剂在艾氏腹水瘤中抑制有丝分裂作用的影响]
Biull Eksp Biol Med. 1988 Mar;105(3):345-7.