Yang G X
Institute of Hepatology, Bethune University of Medical Sciences, Changchun, Jilin.
Zhonghua Zhong Liu Za Zhi. 1991 Jul;13(4):249-52.
The hybridization test for duck hepatitis B virus DNA was performed in 34 ducks with hepatoma from Qidong, Jiangsu province. Among the 34 hepatoma ducks, 18 were positive for DHBV DNA in the serum and 27 were positive in the tumor and/or liver tissue. Tissue sections were stained with Victoria blue nuclear fast red for detecting DHBV surface antigen. Victoria blue positive cells were found in 11 tumors and 15 paratumorous regions of 23 ducks with hepatocellular carcinoma. Although paratumorous regions were positively stained in 3 of 8 ducks with cholangiocarcinoma, all were negative within their tumors. All paratumorous regions and 2 tumor regions of 3 ducks with hepatocellular-cholangiocarcinoma were positive for Victoria blue. The results suggest that duck hepatocellular carcinoma be closely related to DHBV infection.
对江苏省启东市的34只患肝癌的鸭子进行了鸭乙型肝炎病毒DNA杂交试验。在这34只患肝癌的鸭子中，18只血清中的鸭乙型肝炎病毒DNA呈阳性，27只肿瘤和/或肝组织呈阳性。用维多利亚蓝核固红对组织切片进行染色，以检测鸭乙型肝炎病毒表面抗原。在23只肝细胞癌鸭子的11个肿瘤和15个瘤旁区域发现了维多利亚蓝阳性细胞。虽然8只胆管癌鸭子中有3只的瘤旁区域呈阳性染色，但它们的肿瘤内部均为阴性。3只肝细胞-胆管癌鸭子的所有瘤旁区域和2个肿瘤区域维多利亚蓝呈阳性。结果表明，鸭肝细胞癌与鸭乙型肝炎病毒感染密切相关。
