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本文引用的文献

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Enhancing data on nutrient composition of foods eaten by participants in the INTERMAP study in China, Japan, the United Kingdom, and the United States.加强关于中国、日本、英国和美国INTERMAP研究参与者所食用食物营养成分的数据。
J Food Compost Anal. 2003 Jun;16(3):395-408. doi: 10.1016/S0889-1575(03)00043-7. Epub 2003 May 23.
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A validation study on food composition tables for the international cooperative INTERMAP study in Japan.日本国际合作 INTERMAP 研究用食物成分表的验证研究。
Environ Health Prev Med. 2005 May;10(3):150-6. doi: 10.1007/BF02900808.
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Association of dietary supplement use with specific micronutrient intakes among middle-aged American men and women: the INTERMAP Study.美国中年男性和女性膳食补充剂使用与特定微量营养素摄入量的关联：国际多中心动脉粥样硬风险研究（INTERMAP研究）
J Am Diet Assoc. 2005 Jul;105(7):1106-14. doi: 10.1016/j.jada.2005.04.010.
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Association of ferritin and lipids with C-reactive protein.铁蛋白和脂质与C反应蛋白的关联
Am J Cardiol. 2004 Mar 1;93(5):559-62. doi: 10.1016/j.amjcard.2003.11.018.
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Effects of lifestyle on hemostasis, fibrinolysis, and platelet reactivity: a systematic review.生活方式对止血、纤维蛋白溶解和血小板反应性的影响：一项系统评价。
Arch Intern Med. 2003 Oct 27;163(19):2368-92. doi: 10.1001/archinte.163.19.2368.
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Differences in cardiovascular disease risk factors between Japanese in Japan and Japanese-Americans in Hawaii: the INTERLIPID study.日本本土居民与夏威夷日裔美国人心血管疾病风险因素的差异：INTERLIPID研究
J Hum Hypertens. 2003 Sep;17(9):631-9. doi: 10.1038/sj.jhh.1001606.
7
Nutrient intakes of middle-aged men and women in China, Japan, United Kingdom, and United States in the late 1990s: the INTERMAP study.20世纪90年代末中国、日本、英国和美国中年男性和女性的营养素摄入量：INTERMAP研究。
J Hum Hypertens. 2003 Sep;17(9):623-30. doi: 10.1038/sj.jhh.1001605.
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INTERMAP: the dietary data--process and quality control.国际多中心动脉粥样硬化研究（INTERMAP）：饮食数据——过程与质量控制
J Hum Hypertens. 2003 Sep;17(9):609-22. doi: 10.1038/sj.jhh.1001604.
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INTERMAP: background, aims, design, methods, and descriptive statistics (nondietary).国际多中心动脉粥样硬化研究（INTERMAP）：背景、目的、设计、方法及描述性统计（非饮食方面）
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10
Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women.中年女性高血糖负荷饮食与高敏C反应蛋白血浆浓度之间的关系。
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与日本本土人相比，夏威夷日裔美国人血浆纤维蛋白原水平较高所相关的饮食因素。

Dietary factors related to higher plasma fibrinogen levels of Japanese-americans in hawaii compared with Japanese in Japan.

作者信息

Miura Katsuyuki, Nakagawa Hideaki, Ueshima Hirotsugu, Okayama Akira, Saitoh Shigeyuki, Curb J David, Rodriguez Beatriz L, Sakata Kiyomi, Okuda Nagako, Yoshita Katsushi, Stamler Jeremiah

机构信息

Department of Epidemiology and Public Health, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan.

出版信息

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1674-9. doi: 10.1161/01.ATV.0000225701.20965.b9. Epub 2006 May 4.

DOI:10.1161/01.ATV.0000225701.20965.b9
PMID:16675719
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6660157/
Abstract

OBJECTIVE

We investigated whether dietary factors explain higher plasma fibrinogen levels in Japanese emigrants living a Western lifestyle in Hawaii compared with Japanese in Japan.

METHODS AND RESULTS

Plasma fibrinogen and nutrient intakes were examined by standardized methods in men and women 40 to 59 years of age from a Japanese-American sample in Hawaii (100 men and 106 women) and 4 population samples in Japan (569 men and 567 women). Multiple linear regression models were used to examine the relationship between dietary factors and the plasma fibrinogen difference between Hawaii and Japan. Average plasma fibrinogen was significantly higher in Hawaii compared with Japan (P<0.001 in both genders). In multiple linear regression analyses with each dietary variable considered separately, body mass index reduced the plasma fibrinogen difference between Hawaii and Japan by 20.4%; iron intake (mg/1000 kcal) and estimated total sugar intake (%kcal) reduced this difference by 30.0% and 14.4%, respectively. In a model that included body mass index, iron, estimated total sugars, and caffeine (also age and gender), this difference was reduced by 61.3% (from 42.2 to 16.3 mg/dL).

CONCLUSIONS

Higher intake of iron, sugar, and caffeine, in addition to obesity, account largely for higher fibrinogen levels with Westernized lifestyle.

摘要

目的

我们调查了饮食因素是否能解释在夏威夷过着西方生活方式的日本移民与日本本土日本人相比血浆纤维蛋白原水平较高的原因。

方法与结果

采用标准化方法对来自夏威夷的日裔美国人样本（100名男性和106名女性）以及日本的4个人口样本（569名男性和567名女性）中40至59岁的男性和女性进行血浆纤维蛋白原和营养摄入情况检测。使用多元线性回归模型来研究饮食因素与夏威夷和日本之间血浆纤维蛋白原差异的关系。与日本相比，夏威夷的平均血浆纤维蛋白原水平显著更高（男女均P<0.001）。在分别考虑每个饮食变量的多元线性回归分析中，体重指数使夏威夷和日本之间的血浆纤维蛋白原差异降低了20.4%；铁摄入量（毫克/1000千卡）和估计的总糖摄入量（占千卡的百分比）分别使这一差异降低了30.0%和14.4%。在一个包含体重指数、铁、估计的总糖和咖啡因（以及年龄和性别）的模型中，这一差异降低了61.3%（从42.2毫克/分升降至16.3毫克/分升）。

结论

除肥胖外，铁、糖和咖啡因的摄入量较高在很大程度上导致了西方化生活方式下纤维蛋白原水平升高。