Coudray Clotilde, Guitard Evelyne, el-Chennawi Farha, Larrouy Georges, Dugoujon Jean-Michel
Anthropology Centre, CNRS FRE 2960, 37 allées Jules Guesde, 31073 Toulouse, France.
Forensic Sci Int. 2007 Jul 4;169(2-3):260-5. doi: 10.1016/j.forsciint.2006.03.017. Epub 2006 May 4.
DNA typing of 15 short tandem repeat (STR) loci included in the AmpFlSTR Identifiler PCR amplification kit (Applied Biosystems), was carried out in three Egyptian populations of different ethnic groups: the Berbers from the Siwa oasis (in the North-Western Egyptian desert), the Muslims and the Copts from Adaima (Upper Egypt). A total of 297 individuals were typed. After Bonferroni's correction, no deviations from the Hardy-Weinberg equilibrium were observed for all samples at the 15 STR loci. All loci are highly polymorphic and population differentiation tests showed that 7, 10 and 8 out of 15 loci have significant differences between the Berbers and the Muslim samples, between the Berbers and the Copts, and between the two samples from Adaima, respectively. Comparative analyses between our population data and other geographically related populations gathered from the literature were performed.
对AmpFlSTR Identifiler PCR扩增试剂盒(应用生物系统公司)中包含的15个短串联重复序列(STR)基因座进行DNA分型,该研究在三个不同种族的埃及人群中开展:来自锡瓦绿洲(位于埃及西北部沙漠)的柏柏尔人、来自阿达伊马(上埃及)的穆斯林和科普特人。总共对297名个体进行了分型。经Bonferroni校正后,在15个STR基因座上,所有样本均未观察到偏离哈迪-温伯格平衡的情况。所有基因座均具有高度多态性,群体分化测试表明,15个基因座中分别有7个、10个和8个在柏柏尔人与穆斯林样本之间、柏柏尔人与科普特人之间以及来自阿达伊马的两个样本之间存在显著差异。我们将群体数据与从文献中收集的其他地理相关群体进行了比较分析。