Offiah C E, Turnbull I W
Department of Neuroradiology, Hope Hospital, Salford, Manchester, UK.
Clin Radiol. 2006 May;61(5):393-401. doi: 10.1016/j.crad.2006.01.008.
The spectrum of pathology affecting the central nervous system (CNS) in patients suffering from acquired immunodeficiency syndrome (AIDS) is broad and comprises predominantly opportunistic infections and neoplasms. It is estimated that approximately one-third of all patients with AIDS develop neurological complications. The organisms responsible for AIDS are human retroviruses: primarily the human immunodeficiency virus type 1 (HIV). In this review we shall focus on the neurological complications of HIV and AIDS which are applicable to the more frequently occurring intracranial infective organisms. Attention will be paid specifically to those CNS manifestations occurring in the adult HIV and AIDS population as infection in the paediatric HIV and AIDS group, although bearing some similarities, demonstrates some important differences.
获得性免疫缺陷综合征（AIDS）患者中枢神经系统（CNS）受影响的病理谱广泛，主要包括机会性感染和肿瘤。据估计，所有艾滋病患者中约有三分之一会出现神经系统并发症。导致艾滋病的病原体是人类逆转录病毒：主要是1型人类免疫缺陷病毒（HIV）。在本综述中，我们将重点关注HIV和AIDS的神经系统并发症，这些并发症适用于更常见的颅内感染病原体。将特别关注成年HIV和AIDS人群中出现的那些中枢神经系统表现，因为儿科HIV和AIDS组中的感染虽然有一些相似之处，但也表现出一些重要差异。
