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用牛白血病病毒(BLV)对绵羊进行实验性感染。

Experimental infection of sheep with bovine leukemia virus (BLV).

作者信息

Grundboeck M, Buzała E, Szczotka M, Rułka J

机构信息

Laboratory of Cell Pathology, Veterinary Research Institute, Puławy.

出版信息

Pol Arch Weter. 1991;31(1-2):5-13.

PMID:1668211
Abstract

Nine groups of sheep have been experimentally infected with different doses of BLV and by various routes. An immunological response of animals, as well as clinical symptoms of leukosis in the experimental sheep were investigated within several years or months. The animals inoculated with the virus showed appearance of BLV-antibodies in 94 per cent of cases, lymphocytosis in 47 per cent and clinical symptoms of the disease in 33 per cent. In conclusion, sheep have been demonstrated to be animals suitable for experimental study of leukosis.

摘要

九组绵羊通过不同途径感染了不同剂量的牛白血病病毒(BLV)。在数年或数月内,对动物的免疫反应以及实验绵羊白血病的临床症状进行了研究。接种该病毒的动物在94%的病例中出现了BLV抗体,47%出现淋巴细胞增多,33%出现该病的临床症状。总之,已证明绵羊是适合白血病实验研究的动物。

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