Freeman Hugh J, Berean Ken W
Department of Medicine, University of British Columbia, Vancouver.
Can J Gastroenterol. 2006 May;20(5):357-60. doi: 10.1155/2006/893928.
A 52-year-old woman developed severe watery diarrhea, weight loss, anemia and hypoalbuminemia. A localized colon cancer was detected. Subsequently, extensive collagenous mucosal involvement of the small and large intestine was discovered. After resection of the colon cancer, her symptoms resolved. In addition, resolution of the inflammatory process occurred, including the subepithelial collagen deposits. Despite extensive small and large intestinal involvement, both clinical and histological resolution of collagenous inflammatory disease was evident. Collagenous enterocolitis is an inflammatory process that may represent a distinctive and reversible paraneoplastic phenomenon.
一名52岁女性出现严重水样腹泻、体重减轻、贫血和低白蛋白血症。检测发现患有局限性结肠癌。随后,发现小肠和大肠广泛存在胶原性黏膜受累。切除结肠癌后,她的症状得到缓解。此外,炎症过程也得到缓解,包括上皮下胶原沉积。尽管小肠和大肠广泛受累,但胶原性炎症性疾病在临床和组织学上均有明显缓解。胶原性小肠结肠炎是一种炎症过程,可能代表一种独特且可逆的副肿瘤现象。