Derivatives of 2-mercaptobenzenesulphonamide. IX. Synthesis and some pharmacological properties of N- or S-dialkylaminoalkyl derivatives of 2-(4-chloro-2-mercapto-5-methylbenzenesulphonyl)guanidines.

Synthesis and results of preliminary pharmacological examinations such as acute toxicity and influence on circulatory system of 2-(4-chloro-2-mercapto-5-methylbenzenesulphonyl)guanidine hydrochloride derivatives containing N-dialkylaminoalkyl (V-VI, VIIb-VIIIb, Xa), or S-dialkylaminoalkyl (XI-XIII) groups, were described. Compounds VIIa-VIIIa, IX-X, XIa were isolated as free bases.