Nocon M, Keil T, Willich S N
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany.
Aliment Pharmacol Ther. 2006 Jun 1;23(11):1601-5. doi: 10.1111/j.1365-2036.2006.02924.x.
Although gastro-oesophageal reflux disease is a common gastrointestinal disorder, the prevalence rates differ depending on the population studied.
To determine the prevalence of reflux symptoms in the German adult population and any associations with age, gender or socio-economic status.
A total of 7124 subjects were interviewed as part of the German National Health Interview and Examination Survey, which is a representative sample of the general adult population. The prevalence of mild, moderate or severe heartburn or regurgitation was calculated. Logistic regression models were developed to determine the relationship between reflux symptoms and sociodemographic factors such as age, gender and socio-economic status.
The overall prevalence of moderate and severe reflux symptoms was 14% and 4%, respectively. The prevalence increased with age and was highest in the age group 60-69 years with 25% of these subjects reporting moderate or severe reflux symptoms. Being male, it increased the risk of mild, but not of moderate or severe symptoms. Lower socio-economic status was associated with moderate or severe symptoms.
Because of their high prevalence, reflux symptoms are of major public health importance.
尽管胃食管反流病是一种常见的胃肠道疾病，但患病率因所研究的人群而异。
确定德国成年人群中反流症状的患病率以及与年龄、性别或社会经济地位的任何关联。
作为德国国民健康访谈与检查调查的一部分，共对7124名受试者进行了访谈，该调查是一般成年人群的代表性样本。计算了轻度、中度或重度烧心或反流的患病率。建立逻辑回归模型以确定反流症状与年龄、性别和社会经济地位等社会人口学因素之间的关系。
中度和重度反流症状的总体患病率分别为14%和4%。患病率随年龄增加而升高，在60 - 69岁年龄组中最高，该组中有25%的受试者报告有中度或重度反流症状。男性会增加轻度反流症状的风险，但不会增加中度或重度症状的风险。社会经济地位较低与中度或重度症状相关。
由于反流症状的高患病率，它们具有重要的公共卫生意义。
