[大孔树脂对甘草酸的吸附与解吸行为研究]
[The research of the adsorption and desorption behaveior of macroporous resin for glycyrrhizic acid].
作者信息
Wang Yang, Wang Yue-Sheng, Yan Han
机构信息
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2006 Feb;31(4):295-7.
OBJECTIVE
To investigate the performance of static and dynamic adsorption and desorption of the three macroporous resins of AB-8, D-101 and H-103.
METHOD
Compare the adsorption and desorption of the three macroporous resins for glycyrrhizic acid by determining the static adsorption, static desorption, dynamic adsorption and dynamic desorption through detecting the glycyrrhizic acid content by HPLC method.
RESULT
The saturation of AB-8 is 0.75 g (crude drug)/mL (macroporous resins), the best elution reagent is 50% EtoH and it's eluation ration is 68.81% . The saturation of D-101 is 0.75 g (crude drug)/mL (macroporous resins), the best elution reagent is 60%EtoH and it's eluation ration is 64.67%. The saturation of H-103 is 0.5 g (crude drug)/mL (macroporous resins), the best elution reagent is 50%E-toH and it's elution ration is 51.18%.
CONCLUSION
AB-8 and D-101 are the superior absorbents for glycyrrhizic acid.
目的
考察AB - 8、D - 101和H - 103三种大孔树脂的静态及动态吸附与解吸性能。
方法
采用高效液相色谱法检测甘草酸含量，通过测定静态吸附、静态解吸、动态吸附及动态解吸，比较三种大孔树脂对甘草酸的吸附和解吸情况。
结果
AB - 8的饱和吸附量为0.75 g（生药）/mL（大孔树脂），最佳洗脱剂为50%乙醇，洗脱率为68.81%。D - 101的饱和吸附量为0.75 g（生药）/mL（大孔树脂），最佳洗脱剂为60%乙醇，洗脱率为64.67%。H - 103的饱和吸附量为0.5 g（生药）/mL（大孔树脂），最佳洗脱剂为50%乙醇，洗脱率为51.18%。
结论
AB - 8和D - 101是甘草酸的优良吸附剂。
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