Marshall T, Bryan S, Gill P, Greenfield S, Gutridge K
Department of Public Health & Epidemiology, University of Birmingham, Edgbaston, Birmingham, UK.
Heart. 2006 Nov;92(11):1651-5. doi: 10.1136/hrt.2005.072405. Epub 2006 May 18.
To determine the relationship between expressed preferences for drug treatment to prevent coronary disease and several participant and general practitioner characteristics among patients attending coronary risk screening.
Face-to-face interviews with patients. At the first interview, a researcher asked participants to imagine six scenarios representing different levels of pretreatment five-year coronary risk. In each case they were asked whether they would choose treatment that would reduce their coronary risk by 30% of pretreatment risk. At the second interview participants were told their coronary risk and asked whether they would choose treatment. Sociodemographic variables were collected to investigate their relationship to patients' treatment preferences.
Patients identified as likely to be at high coronary risk were invited to attend for risk screening and to participate in the study.
13 practices in the West Midlands.
Participants' preferences varied widely: at the first interview 112 (55.2%) of 203 participants preferred treatment at 3% five-year coronary risk but 31 (15.3%) preferred no treatment even at 30% five-year coronary risk. Age, sex, education and drug treatment history did not affect preferences, but lower social class was associated with preferring treatment at lower risk. Preferences expressed at the second interview were generally consistent with preferences at the first interview (kappa = 0.510, 95% CI 0.380 to 0.639).
Patients attending for coronary risk screening express stable preferences for drug treatment to prevent coronary heart disease. Their preferences vary widely and may be associated with social class.
确定在接受冠心病风险筛查的患者中,对预防冠心病药物治疗的表达偏好与若干参与者及全科医生特征之间的关系。
对患者进行面对面访谈。在首次访谈中,研究人员要求参与者设想六种代表不同治疗前五年冠心病风险水平的情景。在每种情况下,询问他们是否会选择能将冠心病风险降低至治疗前风险30%的治疗方法。在第二次访谈中,告知参与者其冠心病风险,并询问他们是否会选择治疗。收集社会人口统计学变量以调查其与患者治疗偏好的关系。
被确定为冠心病高风险的患者被邀请参加风险筛查并参与研究。
西米德兰兹郡的13家医疗机构。
参与者的偏好差异很大:在首次访谈中,203名参与者中有112名(55.2%)倾向于在五年冠心病风险为3%时接受治疗,但31名(15.3%)即使在五年冠心病风险为30%时也倾向于不接受治疗。年龄、性别、教育程度和药物治疗史不影响偏好,但社会阶层较低与倾向于在较低风险时接受治疗有关。在第二次访谈中表达的偏好通常与首次访谈中的偏好一致(kappa = 0.510,95%置信区间0.380至0.639)。
接受冠心病风险筛查的患者对预防冠心病的药物治疗表达了稳定的偏好。他们的偏好差异很大,可能与社会阶层有关。