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Spontaneous lymphocyte proliferation in HTLV-II infection.

作者信息

Wiktor S Z, Jacobson S, Weiss S H, Shaw G M, Reuben J S, Shorty V J, McFarlin D E, Blattner W A

机构信息

Viral Epidemiology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

出版信息

Lancet. 1991 Feb 9;337(8737):327-8. doi: 10.1016/0140-6736(91)90947-n.

DOI:10.1016/0140-6736(91)90947-n
PMID:1671234
Abstract

We measured lymphocyte proliferation in the absence of antigenic stimulation in 45 HTLV-II infected, 9 HTLV-I infected, and 19 HTLV-I seronegative intravenous drug users (IVDU). Lymphocyte proliferation was higher in IVDUs infected with HTLV-II than in seronegative IVDUs but lower than among those infected with HTLV-I. Higher rates of proliferation were also associated with needle sharing, CD4+ and IL2R+ lymphocyte counts, and HTLV-I antibody titres.

摘要

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